面对困境，她感到绝望。

Miànduì kùnjìng, tā gǎndào juéwàng.

Faced with difficulties, she felt despair.

经济问题使他陷入绝望。

Jīngjì wèntí shǐ tā xiànrù juéwàng.

Economic problems plunged him into despair.

失去亲人让他感到绝望。

Shīqù qīnrén ràng tā gǎndào juéwàng.

Losing loved ones made him feel desperate.